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In 2014, Duprex also wrote in a paper published in Nature that "GOF approaches are absolutely essential in infectious disease research; although alternative approaches can be very useful, these can never replace GOF experiments." He added that, in his view, there were only two reasons for GOF research, the first being to "improve surveillance or to develop therapeutics" and the second being merely to learn "interesting biology."
In that same paper, he also argued that "genetic engineering that is intended and likely to endow a low-pathogenicity, low-transmissibility agent with either enhanced pathogenicity or enhanced transmissibility may be appropriate if the benefits are substantial." He also suggested in this 2014 paper that it "might" be necessary "to enhance pathogenicity of coronaviruses in order to develop a valid animal model for coronaviruses." Years later, during the current coronavirus crisis, Duprex and other officials from the UPMC's Center for Vaccine Research co-developed a Covid-19 research and development "blueprint" for the UN's World Health Organization.
In addition, Duprex's work for DARPA's Prophecy program involved GOF research, as noted above, and the creator of that program, Michael Callahan - former head of DARPA's biodefense therapeutics initiatives, is also a proponent of GOF who believes that such risky research is inseparable from "the research and development enterprise in the life sciences and for biotechnology."
Duprex is also a founding member of Scientists for Science, a group of researchers (most of whom are involved in GOF research) who opposed the GOF moratorium and were "confident that biomedical research on potentially dangerous pathogens can be performed safely and is essential for a comprehensive understanding of microbial disease pathogenesis, prevention and treatment." Another of the group's founding members is Yoshihiro Kawaoka, whose controversial GOF experiments that made pathogenic viruses more deadly have garnered considerable media attention.
When the moratorium on GOF was lifted in December 2017, Duprex called it a "sign of progress," adding that "on a personal level I'm really pleased these NIH funded scientists [conducting GOF research] get some clarity." As previously mentioned, he became the Center for Vaccine Research's director less than three months later, in March 2018.
The "Darkest Winter" LoomsAfter a cursory examination of the background of UPMC, its Regional Biocontainment Laboratory, and the man directing its Center for Vaccine Research, the question about the nature of the Corona-thrax experiment becomes: Is this yet another ill-advised experiment by a lab led by a GOF enthusiast and fueled by a feeding frenzy over the billions of dollars thrown by the government and other entities into Covid-19 research? Or is there perhaps a more nefarious motive to genetically engineering something as bizarre as Corona-thrax?
While the latter question may appear conspiratorial, it is worth pointing out that the institutions most likely to have been the sources for the anthrax used in the 2001 anthrax attacks were conducting GOF research on anthrax funded by the Pentagon and the CIA that was justified as "improving" the controversial anthrax vaccine known as BioThrax.
For instance, Battelle Memorial Institutea Pentagon and CIA contractorbegan genetically engineering a more virulent form of anthrax "to see if the [anthrax] vaccine the United States intends to supply to its armed forces is effective against that strain." While these experiments were going on, the embattled manufacturer of the anthrax vaccine now known as Emergent Biosolutions, entered into a contract with Battelle that gave Battelle "immediate exposure to the vaccine" it was using in connection with the genetically modified anthrax program.
As noted in Part II of this series, BioPort was set to lose its Pentagon contract for anthrax vaccine entirely in September 2001, and the entirety of its anthrax vaccine business was rescued by the 2001 anthrax attacks, which saw concerns over BioPort's corruption and its horrendous safety track record replaced with fervent demands for more of its anthrax vaccine. Furthermore, as noted in detail in Part III of this series, Battelle was the most likely source of the anthrax used in the 2001 attacks. The ties between UPMC's Center for Biosecurity, Battelle, and Emergent Biosolutions will be discussed in the next installment in the series.
What is also notable about these Corona-thrax experiments occurring at UPMC are the ties of UPMC's RBL and Center for Vaccine Research to another key component of the center's "biodefense" complex, the UPMC Center for Biosecurity. As previously mentioned, the people recruited to head this center at its founding in 2003 were intimately involved in the 2001 bioterror simulation Dark Winter, namely Tara O'Toole and Thomas Inglesby.
While leading the UPMC's Center for Biosecurity, O'Toole and/or her successor Inglesby engaged in other notable bioterror simulations, including one that took place last year Event 201, which eerily predicted the coronavirus crisis that began this year. Inglesby, who is also the director of the Johns Hopkins Center for Health Security in addition to his post at UPMC, was the moderator at Event 201.
Though Event 201 has garnered considerable scrutiny in recent months, another but less well-known exercise in 2018 that involved O'Toole and Inglesby, examined how a bioterror attack involving a genetically engineered pathogen could trigger a Continuity of Government (CoG) scenario, a government roadmap for the imposition of martial law in the United States. As other investigative series of mine have noted, there have recently been a myriad of intelligence agency-linked simulations that predict the imminent imposition of martial law in the United States following the 2020 election.
It is also notable that George W. Bush's controversial and classified update to CoG plans in 2007, known as Executive Directive 51, was directly inspired by Dark Winter, and Barack Obama's subsequent executive orders on CoG gave near-complete control of American infrastructure to the Department of Homeland Security in a such a situation. At the time Obama issued those executive orders, O'Toole was the DHS undersecretary for science and technology and also influenced those updates to the CoG plans. O'Toole is currently the executive vice president of the CIA's In-Q-tel.
The simulation known as Clade X will be examined in greater detail in the next installment of this series as will the numerous and recent "predictions" from US government sources, controversial billionaires such as Bill Gates, and a web of individuals tied to UPMC who have warned that a bioterror attack or related public health catastrophe is set to take place in the United States in the latter half of 2020. As one high-ranking government official put it earlier this year, this allegedly imminent event will result in "the darkest winter in modern history."
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