Send a Tweet
Most Popular Choices
Share on Facebook 10 Share on Twitter 8 Share on LinkedIn Share on Reddit Tell A Friend Printer Friendly Page Save As Favorite View Favorites
General News

Why Were These Drugs Approved?

By       Message Martha Rosenberg       (Page 1 of 2 pages)     Permalink    (# of views)   16 comments

Related Topic(s): ; ; ; ; ; ; ; ; ; ; (more...) , Add Tags  (less...)
Add to My Group(s)

Must Read 9   Well Said 7   News 5  
View Ratings | Rate It

opednews.com Headlined to H2 5/11/12

Author 1353
Become a Fan
  (84 fans)
- Advertisement -

Like Vioxx, Merck's expensive "super aspirin" that caused thousands of cardiovascular events before being recalled, Merck's Fosamax, the first bisphosphonate bone drug, flew out of the FDA with only a six-month review.

 

And like Vioxx, the true dangers of the drug class (that includes Fosamax, Boniva and Reclast) only surfaced after being "tested" on the guinea pig know as John Q Public.

 

- Advertisement -

Now, people are asking why the bone drugs were ever approved.

 

Like Vioxx, there were early indications of Fosamax's risks but they did not prevent wide marketing.   Merck received 1,213 adverse-effect reports soon after the drug's approval, which included 32 hospitalized patients with adverse esophageal effects, 17 with "severe" effects, and two who were "temporarily disabled," reported the New England Journal of Medicine. One woman who took Fosamax and only remained upright for 30 minutes not 60 minutes as directions say, had to be admitted to the Mayo Clinic with "severe ulcerative esophagitis affecting the entire length of the esophagus" and had to be fed intravenously.

- Advertisement -

 

And there were other safety signals. Bisphosphonate patients were found to be at greater risk for osteonecrosis of the jaw--death of the jawbone--after in-office dental procedures.   They were found to be at greater risk for irregular heart beat, intractable pain and at double the risk of esophageal cancer, according to medical reports.

 

Then, in 2010, after millions of women were taking the widely advertised bisphosphonates, studies revealed they sometimes caused the very fractures they were supposed to prevent!


Thanks, Big Pharma
(Image by Martha Rosenberg)
  Permission   Details   DMCA
 

- Advertisement -

"Long-term use of osteoporosis drugs linked to hip breaks," said USA Today . "Increased risk of fracture with bisphosphonates," said the Associated Press. "Drugs to build bones may weaken them," said the New York Times, who reported that the thigh bones of patients on bisphosphonates have "simply snapped while they were walking or standing," after "weeks or months of unexplained aching."

 

Soon after the FDA met in 2011 to determine how long patients could safely remain on the drugs (assuming they were safe at all), an article in New England Journal of Medicine suggested that 90 percent of women who have been getting bone scans, devised by Big Pharma to sell bone drugs say published reports, did not need them. Oops.

 

Next Page  1  |  2

 

- Advertisement -

Must Read 9   Well Said 7   News 5  
View Ratings | Rate It

opednews.com

Martha Rosenberg is an award-winning investigative public health reporter who covers the food, drug and gun industries. Her first book, Born With A Junk Food Deficiency: How Flaks, Quacks and Hacks Pimp The Public Health, is distributed by Random (more...)
 

Martha Rosenberg Social Media Pages: Facebook page url on login Profile not filled in       Twitter page url on login Profile not filled in       Linkedin page url on login Profile not filled in       Instagram page url on login Profile not filled in

Go To Commenting
The views expressed herein are the sole responsibility of the author and do not necessarily reflect those of this website or its editors.
Writers Guidelines
Contact AuthorContact Author Contact EditorContact Editor Author PageView Authors' Articles
Support OpEdNews

OpEdNews depends upon can't survive without your help.

If you value this article and the work of OpEdNews, please either Donate or Purchase a premium membership.

STAY IN THE KNOW
If you've enjoyed this, sign up for our daily or weekly newsletter to get lots of great progressive content.
Daily Weekly     OpEdNews Newsletter
Name
Email
   (Opens new browser window)
 

Most Popular Articles by this Author:     (View All Most Popular Articles by this Author)

Grassley Investigates Lilly/WebMD link Reported by Washington Post

The Drug Store in Your Tap Water

It's the Cymbalta Stupid

Are You Sure You're Not Psychotic Asks Shameless Drug Company?

Another Poorly Regulated "Derivative"--the Antidepressant Pristiq

MRSA and More. Antibiotics Linked to Obesity and Allergies, Too