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Clock is ticking: 26 months left to meet AIDS 90-90-90 targets

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The World Health Organization (WHO) guidelines 2016 as well NACO India guidelines recommend routine viral load monitoring should be carried out at 6 months, at 12 months and then every 12 months thereafter if the patient is stable on ART. It is very important to scale up viral load testing in India to monitor the viral load suppression.

Undetectable = Untransmittable

Scientific evidence has shown that if every PLHIV who is on ART has undetectable viral load (less than 20 copy/ml) his/her risk of transmitting HIV becomes negligible, and the person can lead a normal healthy life commensurate to the principle "Undetectable = Untransmittable". VLT in India were done only at 10 national reference laboratories for suspected treatment failure cases. In 2016-17, only around 16,500 PLHIV who were on ART received VLT, but this capacity is escalated to 160,000 VLT in public-private partnership initiative. As per WHO and NACO guidelines, every PLHIV should have received the VLT. With such a small VLT capacity, it is not known how many of the documented 11.81 lakhs people on ART are virally suppressed.

"If every PLHIV needs a viral load test even once a year, then we need to scale up VLT capacity to conduct over 2 million (21.4 lakh) tests every year. How would India meet the goal of achieving viral load suppression for 90% of those PLHIV who are receiving ART by 2020 if business as usual continues?" asks Dr Ishwar Gilada. He said that efforts of National AIDS Control Programme (NACO) to move from targeted VLT to routine VLT for all patients on ART is a step in the right direction. This will help in earlier and more accurate detection of treatment failure. A viral load test will be conducted for all patients at 6 and 12 months after initiation of ART. All second/third line patients will be tested every 6 months and the first line patients will be tested annually after 12 months of ART initiation.

Dr GD Ravindran, co-chair of 11th ASICON said that in 2017, Karnataka had 2,47,413 PLHIV (1,23,821 women), among who 1,55,411 (62.8%) were receiving ART. AIDS related deaths have declined in Karnataka state by 68% between 2010-2017 to 8450. Despite a decline of 46% in new HIV infections in the state, we still saw 5008 new HIV infections in 2017."

Dr Glory Alexandar, co-chair of 11th ASICON said to CNS (Citizen News Service) that, "Regarding prevention of parent to child transmission of HIV (PPTCT), out of the estimated 22677 pregnant women living with HIV in India in 2017, only 13716 of them were receiving ARVs for PPTCT (60% coverage). In Karnataka however PPTCT coverage in 2017 was around 70% at 1421 against need of 1951. India aims to eliminate HIV transmission from parent to child. We need to accelerate progress towards these goals as well as maintain surveillance of HIV in pregnant women to ensure we do not risk reversing the progress made so far."

ASICON 2018 will present the latest developments in diagnosis, prevention and management of HIV, and associated co-infections/ opportunistic infections. Recent advances in the vaccine, early treatment, cure research, diagnostics and future drugs will also be discussed. Academic partners of 11th ASICON include: government of India's National AIDS Control Organization (NACO), United Nations joint programme on HIV/AIDS (UNAIDS), Medical Council of India, CAPRISA, Gilead Sciences Inc., PHO, Asha Foundation among others.

Shobha Shukla, CNS (Citizen News Service)

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