The human race is fundamentally, socially defective.
Politics is whistling in a dark that's not listening and institutionalized religion appeals only to two digit IQ's.
But our suffering is real and more than anything else it defines the human condition.
The essence of the problem is that we absolutely don't know how to live together in ways which are sane, rational, and kind. But even that's too simplistic, because the problem is even beyond our ability to "define" it. All we DO know is that since the beginning of recorded history, practically all of us have been living in chronic misery.
We may have some vague sense of what our lives could be like if we somehow solved the "social problem" (can we put it like that?). But the torturing heart of this is that we HAVE NO CLUE how to do it.
Sure, we have a list of crapolas like politics, religion, and sometimes even revolution, but alas, they are much ado about nothing. Indeed, if we are really honest (which we are maybe 0.01% of the time), we will acknowledge that these things always have been, are now, and always will be more part of the problem than the solution.
It's hard to imagine ANYONE on planet Earth who still thinks "politics" is going to radically socially change anything. Of course, that's exactly what most of us actually DO believe, so we keep (in the words of an ancient Chinese Zen master) "washing off blood with blood."
Indeed, the worst thing about all our pitiful attempts to solve the social problem is that all these attempts ARE THEMSELVES an expression OF the problem.