In 2008, Stowe was the primary investigator for a National Institutes of Health grant where the stated purpose was "to stimulate vigorous debate with the emphasis on the reproductive safety of antidepressant medications," according to a June 2, 2009 letter to the president of Emory from Grassley.
Glaxo paid Stowe $154,400 for fifty-seven promotional talks in 2007. He also received $99,300 from Glaxo in the first ten months of 2008 for thirty-eight talks for antidepressants, according to Grassley.
During a deposition, Stowe testified that around "80% of his Emory salary ($187,000) comes from his NIH grants," the letter notes. His total Emory salary was $232,000.
In a June 11, 2008 statement on the Senate Floor, in describing his investigation, Grassley said, "I have been looking at how drug companies try and influence medical care in America. Companies can do this by, for example, creating studies favorable to their drugs, by hiring doctors to promote their products, and in some cases even intimidating critics of their drugs."
On this date, Grassley was announcing his investigation of Glaxo regarding revelations in reports filed in Paxil suicide litigation by Dr Joseph Glenmullen, showing the company had manipulated the numbers on adverse events related to suicidality in clinical trials all the way back in 1989, before the drug was FDA approved, to make it appear that Paxil did not increase the risk of suicidal behavior when, in fact, trial subjects on Paxil were eight times more likely to attempt or commit suicide than patients taking a placebo.
"So what did GlaxoSmithKline do with these reports?" Grassley said. "Well, the company tried to hide them."
"They went to the judge and asked to have Dr. Glenmullen's report and all the confirming documents placed under seal-that means that no member of the public could see them," he said. "In fact, Glaxo has been doing everything possible to ensure that this information remains under court seal."
"It seems to me that GlaxoSmithKline tried to hide these reports because they seem to demonstrate what the company knew-that Paxil was associated with an increased risk of suicide based on the company's own studies," Grassley noted.
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