Cognitive yes yes
Gastrointestinal yes yesFigure 1, (1,3,4)
Does a common denominator of AChEi exposure explain such mirror imagery?
Again, potent AChEis emanate from particular groups of fungi often associated with incidents of SBS, or more specifically, from particular mycotoxins within these groups.(5,6,7) However, to date and in contrast to GWI, it appears research has yet to address the potential health effects this AChEi exposure may generate or the explanation for SBS it may provide.
We believe the SBS question may well be associated with mycotoxins such as Territrem B (TRB), "a potent and irreversible inhibitor of acetylcholinesterase (AChE)",(5) and one which has been found to exist in both Penicillium sp FO-4259 (6) and Aspergillus terreus.(5) This is particularly significant given that both Penicillium and Aspergillus are commonly associated with SBS,(7) though questions remain as to how broadly AChEis generally, and mycotoxins such as TRB particularly, may be found within each genus, as well as within other indoor molds.
Figure 2, (6)
Low-Level Exposure and Chronic Symptoms
Questions regarding the impact of repeated low-level exposures to potentially toxic agents exist within the circumstances of both GWI and SBS. For GWI, "evidence of chronic and delayed consequences to physiological systems from repeated low-level AChEi exposure" was found, with it being added that "evidence for persistent and delayed effects of low-level exposure is accruing".(1)