During FDA hearings on SSRIs back in February 2004, researchers presented evidence showing SSRIs to be little or no more effective than placebos. Psychologist, David Antonuccio, from the University of Nevada Medical School, was part of a team that analyzed 12 studies and told the committee, "Our conclusions were that the advantages of the antidepressants in children were so small and so trivial as to be clinically insignificant."
"In order to evaluate the cost effectiveness of antidepressant use in children, the committee must consider the benefits, as well as the risks," Dr Antonuccio testified.
"Clinically meaningful benefits have not been adequately demonstrated in depressed children," he said, "therefore, no extra risk is warranted."
On July 21, 2004, the Journal of the American Medical Association, also reported that there was a significantly higher risk of suicide and suicidal thoughts during the first 9 days of treatment with SSRIs, and that children who were first starting treatment were 4 times more likely to think about suicide, and 38 times more likely to commit suicide and that children as young as five had committed suicide while taking these drugs.
In the fall of 2004, the FDA ordered drug makers to post a black box warning on SSRIs, the most serious warning a drug can carry. The problem is black box warnings do not stop doctors from prescribing SSRIs to children.
"Unfortunately," says Senator Charles Grassley, who has been conducting oversight of the FDA from his position as chairman of the Senate Finance Committee, in response to the news of a black box warning on SSRIs, "the poor performance data for these drugs has been coupled with the very compelling and heart-wrenching testimony from parents and other public witnesses who identify the medications themselves as triggering tragic and unexpected suicides and suicidal behavior among users."
"I understand," he continued, "that the testimony yesterday even included discussions about patients who had not been suffering from depression, yet were prescribed these powerful drugs by physicians who may perhaps have been all too ready to medicate their patients."
When reviewing studies that had previously been suppressed, the FDA found one trial on the SSRI, Paxil, with a "possibly suicide-related" risk of 6.5 percent, and a 5.4% risk of suicide attempts, compared to a 1.1% and zero, respectively in patients taking a placebo.
In fact, in 2004, Paxil maker, Glaxo, was sued by New York State Attorney General, Eliot Spitzer, for committing fraud by hiding studies that "not only failed to show any benefit for the drug in children but demonstrated that children taking Paxil were more likely to become suicidal than those taking a placebo."
In September 2005, British public health officials instructed doctors to never prescribe SSRIs to children without providing psychotherapy as well. Physicians were also told to never prescribe the drugs without trying other alternative drugs first, and to not prescribe Effexor or Paxil to children under any condition.
In addition to all the other problems with SSRIs, previously suppressed studies show the drugs are addictive. In June 2003, Glaxo, removed labels that said Paxil was not habit-forming after thousands of patients claimed they had become addicted to the drug.
Experts warn that SSRIs can also cause children to become violent as well as suicidal. According to Dr Julian Whitaker, SSRIs cause akathisia, a mental and physical agitation that sparks self-destructive, violent behavior, and induce disassociative reactions that make patients who take the drugs insensitive to the consequences of their behavior.
This is the type of drug, he says, that Eric Harris was taking when he killed his fellow students at Columbine.
Kip Kinkel was on Prozac, Dr Whitaker says, when he killed his parents and then went to his high school in Oregon, and killed two students and wounded 22 others, and says Joseph Wesbecker was also taking Prozac when he killed 7 people at a printing plant in Kentucky, before taking his own life.
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