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August 31, 2006 at 06:33:10

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Big Pharma Bankrupting US Health Care System

by Evelyn Pringle     Page 1 of 5 page(s)

www.opednews.com

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Big Pharma is bankrupting the nation's health care system by convincing prescribing doctors to over-medicate patients with expensive psychiatric drugs and then send the bills to government programs like Medicaid and Medicare.

The peddling of the new generation of psychiatric drugs that include the selective serotonin reuptake inhibitors antidepressants (SSRIs), and atypical antipsychotics that began arriving on the market in the late 1980s, has become a cottage industry in the US.

Between 1986 and 2004, the sale of antidepressants went from $240 million to $11.2 billion and the sale of antipsychotic drugs rose from $263 million in 1986 to $8.6 billion in 2004.

These two classes of drugs combined went from $500 million to nearly $20 billion in 2004, which translates to a 40-fold increase, according to award winning journalist, Robert Whitaker, author of Mad In America.


A University of Georgia study published in the June 2006 issue of Journal of Clinical Psychiatry, found that three-quarters of people prescribed antidepressant drugs receive the medications for a reason not approved by the federal FDA.

The researchers reviewed records on drugs prescribed to 107,000 Georgia Medicaid recipients in 2001. The researchers used Medicaid data because it is comprehensive and easily accessible, and said the results are likely to be comparable in other states.

The study examined rates of off-label prescribing for drugs that act on the central nervous system and found that 75% of antidepressant recipients and 64% of antipsychotic recipients these received the drugs off-label.


While study authors Dr Hua Chen and Professor Jack Fincham acknowledged that there are legitimate uses for off-label prescribing, they said that in many cases doctors write off-label prescriptions based on limited or anecdotal evidence.

"Most off-label drug mentions have little or no scientific support," said study co-author Jack Fincham, Professor of Pharmacy Care at the University of Georgia College of Pharmacy to Doctor's Guide News on July 25, 2006. "And when I say most," he said, "it's like 70% to 75%."

"Many patients," he noted, "have no idea that this goes on and just assume that the physician is writing a prescription for their indication."

"Physicians have the right to prescribe any medication off label," Dr Chen said, "but they also have the responsibility to inform patients that this medication is being used off label."

Study leader, Dr Chen, an assistant professor at the University of Houston, said the findings reveal a significant gap in the nation's drug safety system. The FDA approval process is widely regarded as the world's most rigorous, she noted, but said off-label prescribing regularly exposes consumers to drugs that are untested for their condition.

"There's a big gap between this very strict approval process and this very liberal utilization practice," Chen said. "Something must be done to fill this gap."

Professor Fincham, author of the book, "Taking Your Medicine: A Guide to Medication Regimens and Compliance for Patients and Caregivers," told Doctor's Guide that considering the aging population and the increasing likelihood of off-label prescribing with age, the number of people receiving off-label drugs will likely increase in the coming years.

According to Dr Chen and Professor Fincham, the off-label use of central nervous system drugs can account from anywhere from 25% to 80% of a drug's annual sales.

Drug makers have found ways to influence prescribers who tend to the elderly in nursing homes to funnel Medicare funds to Big Pharma through senior citizens. In one 2003 study published in the Archives of Internal Medicine, researchers found that 75% of long-term care elderly residents were receiving psychotropic medications.

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Evelyn Pringle is a columnist for OpEd News and investigative journalist focused on exposing corruption in government and corporate America.

The views expressed in this article are the sole responsibility of the author
and do not necessarily reflect those of this website or its editors.

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1 comments


Zyprexa dangers

Thanks Evelyn Pringle for the heads up on Eli Lilly ZYPREXA Zyprexa (Olanzapine) is Lilly's largest seller. It used to be the first-place atypical antipsychotic in the U.S. but has dropped to third. This is probably because doctors and patients have learned, through the NIH CATIE study and through thousands of lawsuits, that it has the most dangerous side effects of all the drugs in its class. It causes diabetes, hyperglycemia, and death. 8000 plaintiffs settled with Lilly in 2005 and are still waiting for payment. Many states have sued Lilly for alleged fraud, for not revealing its side effects, and for compensation to their state's Medicaid programs for the costs of the drug as well as the costs involved in caring for people who got such conditions as diabetes from the drug. Lilly has also been charged with alleged fraud in off-label marketing of the drug for children. Many individual lawsuits remain outstanding and will begin to be heard once the 8000 plaintiff suit has been finalized. Lilly states that it will "vigously defend" itself against these individual lawsuits, but a number of them are for death allegedly caused by this drug -- Daniel Haszard ~ zyprexa caused my diabetes http://www.zyprexa-victims.com

by Danny Haszard (2 articles, 0 quicklinks, 0 diaries, 61 comments [7 recommended, 0 rejected]) on Thursday, Aug 31, 2006 at 8:16:59 AM

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