How an outsider bucked prevailing Alzheimer's theory, clawed for validation - STAT

Even as potential Alzheimer’s drugs failed, researchers with fresh approaches struggled to get funded and to get studies published in top journals.

It was an “unorthodox hypothesis” that might “fill flagrant knowledge gaps,” wrote one reviewer, but another said the planned work might add little “to what is currently known.” A third complained that although Moir wanted to study whether microbes might be involved in causing Alzheimer’s, no one had proved that was the case.