World TB Day, 24 March 2010
In this year 2010, which has been declared as Year
Lung, it is indeed a much-awaited welcome news that International Union
Tuberculosis and Lung Disease (The Union) is to launch an International
of 9-month MDR-TB treatment regimen. The need for accessible, effective
multidrug-resistant tuberculosis treatment is urgent, as the incidence
MDR-TB continues to rise, and extensively drug-resistant TB (XDR-TB) has
reported in 57 countries. In response, the International Union Against
and Lung Disease (The Union) is launching a trial of a 9-month treatment
regimen that has demonstrated cure rates exceeding 80% in a pilot
While tuberculosis has been curable for more than 60 years, drug-resistant strains are far more difficult and costly to treat. Currently used treatment regimens can take up to two years to complete, placing a heavy burden on both patients and health systems.
The Union's evaluation of a standardised treatment regimen of anti-tuberculosis drugs for patients with multiple drug-resistant tuberculosis or STREAM will seek to determine whether a regimen developed and implemented by the Damien Foundation and the Institute of Tropical Medicine, and used with notable success in Bangladesh, can be used in different settings with comparable results.
"Obviously, this regimen represents a significant difference in time and resources for all involved", says Dr Nils E Billo, Executive Director of The Union. "But any treatment strategy must be carefully evaluated to ensure the most effective and feasible approaches are implemented, particularly in low-income settings where MDR-TB is most prevalent."