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Ghostbusting in Paxil Birth Defect Litigation

By       Message Evelyn Pringle       (Page 1 of 11 pages)     Permalink    (# of views)   No comments

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A month before the first Paxil birth defect trial against GlaxoSmithKline was set to begin, the Associated Press ran the headline, "Glaxo Used Ghostwriting Program to Promote Paxil," in reporting on a program called "CASPPER," which allowed doctors to "take credit for medical journal articles mainly written by company consultants."



"Drug companies frequently hire outside firms to draft a manuscript touting a company's drug, retain a physician to sign off as the author and then find a publisher to unwittingly publish the work," the Associated Press said on August 19, 2009. "Drug company salespeople often present medical journal articles to physicians as independent proof that their drugs are safe and effective."

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Between 2000 and 2002, articles from the CASPPER program appeared in five medical journals. On August 21, 2009, Jim Edwards on BNET, described the CASSPER ghostwriting brochure. The document shows that the intent of CASSPER was to flood the market with ghostwritten information, he said. It stated: "Paxil Product Management has budgeted for 50 articles for 2000."



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The trial in Kilker v Glaxo ended on October 13, 2009, with a jury in Philadelphia finding that Glaxo "negligently failed to warn" the doctor treating Lyam Kilker's mother about Paxil's risks and the drug was a "factual cause" of Lyam's heart defects. The family was award $2.5 million.


Ghostwriting 101


The world-renowned neuropsychopharmacologist from the UK, Dr David Healy, testified as an expert witness for the plaintiffs in the Kilker trial.

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While testifying, Healy explained the process of ghostwriting to the jury. He said ghostwriting probably began seriously in the 1980s. "It's where an article appears under the name of usually a fairly distinguished person in the field," he testified.


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Evelyn Pringle is an investigative journalist and researcher focused on exposing corruption in government and corporate America.

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