An aspartame reactor had been taking thyroid hormone several years. After avoiding aspartame products, he noted "My replacement thyroid dose, which had been steadily increasing for the last few years, dropped by 30 percent. My doctor was quite surprised, and had no other explanation for it".
F. Female Hormone Replacement Therapy
Patients with aspartame disease expressed firm convictions about interactions involving female hormone replacement therapy.
Case IX-I-5
A 40-year-old saleswoman consumed considerable diet sodas and other aspartame products, especially during the summer. She supplemented her description of reactions in the survey questionnaire with a two-page analysis of major changes when taken in conjunction with Premarin/Provera. They included cloudy vision, dizziness, tenderness and tingling of the feet, joint pains, numbness of the lower limbs, headache, "foggy thinking," confusion, slurred speech and extreme fatigue. She took as many as 18 ibuprofen tablets daily to obtain relief of her constant pain. Extensive neurologic studies - including electromyography, nerve conduction studies, x-rays and MRI scanning - failed to revel a cause.
Considering a possible connection to the hormonal therapy, she reduced Premarin by half and quit Provera. There was considerable relief from the joint pain and muscle aches within two days, along with cessation of her neuropathic symptoms. After then avoiding all aspartame products, she wrote, "I felt IMMEDIATE relief within two days of what remained of the lumbar ache, muscle aches, foggy thinking, dizziness, and cloudy vision. All these improvements continue in the week since. Walking seems less of an effort; hip pain improved."
G. Methyldopa (Aldomet)
There have been references to enhancement of seizures and other disorders in patients receiving methyldopa hypertension who also consumed aspartame. Seven of the initial 397 reactors completing the questionnaire were taking this drug when they experienced aspartame disease. Maher and Kiritsy (1987) demonstrated that aspartame administration decreases the entry of methyldopa into rat brain.
Representative Case Report
Case IX-I-6
A 67-year-old retired hypertensive woman had been treated with methyldopa. She experienced three unexplained seizures while drinking one can of diet cola and eating various aspartame puddings daily. The convulsions stopped when she avoided aspartame products, as did her sensitivity to noise and attacks of rapid heart action.
H. Analgesics
Lidocaine (Xylocaine) is an important drug used for local anesthesia and the treatment of ventricular arrhythmias in intensive care units. Alterations of its pharmacology by aspartame require study.
Kim et al (1987) reported that the intraperitoneal administration of aspartame significantly reduced the 50 percent convulsion dose of lidocaine. They indicated that PKU patients and asymptomatic PKU heterozygotes may be more sensitive to the toxic effects of this and relate3d local anesthetics.
Next Page 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11
(Note: You can view every article as one long page if you sign up as an Advocate Member, or higher).
1
1
1
