When 24 patients on polypharmacy combinations of Seroquel, Zyprexa and other antipsychotics were reduced to only one drug -- monotherapy -- there was no worsening of symptoms or increased hospitalizations in 23. Not only did patients not deteriorate, their waist circumferences and triglycerides improved, say the researchers as drug interactions, side effects and cost of treatment declined.
"These are interesting data," said a young female psychiatrist viewing the poster. "Normally clinicians are afraid to take such patients off polypharmacy."
So is pharma.
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