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General News    H4'ed 3/3/10

Cold Case Files - Paxil Birth Defects

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In May 2009, a paper was published by a Doctor Sloot and the complete version of the study came out in September 2009. During closing arguments, Tracey told the jury, the "Sloot study is probably the single most problematic document in this case for them because it could have easily been done."


"They would have known that the drug was a clear teratogen. It was more powerful than cocaine," he said. "And it was more powerful a teratogen than even the control or as powerful as the control retinol that everybody in this courtroom, everybody that has testified, has said that drug is a teratogen."


"And had GSK done the studies that Baldwin told them they should do, or a study like Sloot, any time before they started marketing," he told the jury, "we wouldn't be here."


Retinol is an active ingredient in Accutane, a pregnancy Category X drug, meaning it is known to cause birth defects and is not to be used by pregnant women.


During his testimony, Healy was asked to tell the jury what the Sloot study was seeking to do.


"Schering-Plough had acquired a different European company called Organon who had a number of drugs which were serotonin reuptake inhibiting drugs," he explained.


"One of the things that Schering-Plough wished to find out was could they bring any of these drugs to the market," he said.


"What they then did was to do reproductive toxicology studies on these drugs that were new to them, plus on, I believe, all of the SSRI drugs that were on the market, plus a number of drugs which also inhibit serotonin reuptake, like cocaine, and they threw into the mix one or two more drugs, one that was known not to cause birth defects and one that was known to cause birth defects closely related to Accutane," he told the jury.


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Evelyn Pringle is an investigative journalist and researcher focused on exposing corruption in government and corporate America.
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