The bottom real-politik line, as defined by Khamenei himself, is that the US/Iran Wall of Mistrust seems destined to remain in place -- far beyond the nuclear agreement. Multiple Washington factions, not to mention the Pentagon, continue to regard Iran as a "threat," a rogue nation, or evil incarnate, while Tehran sees Washington as "the heart of global arrogance."
So the geopolitical path ahead for Iran -- whatever happens after the deal is ratified in both capitals and the package of sanctions starts to unravel by late 2015/early 2016 -- is Eurasia integration, as I outlined more here.
That implies closer cooperation -- and a three-way strategic partnership -- between Iran, Russia and China. And that further implies the "Bomb Iran" dogs of war getting even more bloodthirsty.