Elsewhere, Seroquel for PTSD gets good reviews.
"These data are encouraging for adjunctive treatment with a second-generation [atypical] antipsychotic in patients who have partially responded to an SSRI or an SNRI [antidepressants]," says the American Psychiatric Association's March 2009 Practice Guideline for the Treatment of Patients with Acute Stress Disorder and Posttraumatic Stress Disorder. Matthew J. Friedman, one of its four authors, is executive director of the U.S. Department of Veterans Affairs National Center for PTSD -- and an AstraZeneca consultant.
"Quetiapine improves sleep disturbances in combat veterans with PTSD," wrote Mark Hamner in a 2005 Journal of Clinical Psychopharmacology article. Hamner is medical director of the PTSD clinical team at the Ralph H. Johnson Department of Veterans Affairs Medical Center in Charleston, SC -- and an AstraZeneca consultant.
"Atypical antipsychotics also have an emerging place in PTSD pharmacology, particularly for symptoms of paranoia, intense hypervigilance, arousal, extreme agitation, dissociation, psychotic-type flashbacks, and brief psychotic reactions," writes Cynthia M. A. Geppert in a 2009 Psychiatric Times article. She is chief of consultation psychiatry and ethics at the New Mexico Veterans Affairs Health Care System -- and recipient of three AstraZeneca grants.
Meanwhile, critics and activists ask: What protections are afforded to veterans enrolled in Seroquel studies -- some combining Seroquel with other drugs -- that AstraZeneca-funded doctors conduct at VA medical centers?
Many say that Big Pharma, embedded in academic institutions, medical schools, military medicine, government entitlement programs and the FDA itself is too big to regulate, like Wall Street firms. But others say the incarceration of VA Chief of Psychiatry Richard Borison in 1998 is proof the system works.
Of course, he will be out soon.
The original version of this story appeared on Alternet.org
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