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General News    H4'ed 3/3/10

Cold Case Files - Paxil Birth Defects

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Rats are only pregnant for about 22 days, or 7 to 8 days per trimester, she said.


Wier's study was not designed to find out whether Paxil was a teratogen. It was a behavioral study, "which the ultimate goal was to keep pups alive so that you could look at changes in their behavior," she pointed out.


"They designed the study to fail," Tracey told the jury in his opening statement.


A 1997 document stated the doses "have been adjusted accordingly and the risk is now considered as minimal and acceptable," he said in closing arguments.


But the study did have rats that died with birth defects. Specifically, a ventricular septal defect (VSD), was found in an edematous (swollen) rat; one of the same defects that Lyam Kilker was born with.


The conclusions in the report did not disclose whether the rat with VSD was born to a mother exposed to Paxil. "It was in the text and it was also in appendix 9," Parisian said.


She testified that the 1980 Ferrosan study also had two edematous rats but they were not autopsied. There is "no information as to why those two rats were edematous," she stated, "but the company listed them as major malformations."


"They also had malformations in their rabbit studies," Parisian reported.


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Evelyn Pringle is an investigative journalist and researcher focused on exposing corruption in government and corporate America.
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