You know, Risperidone (Risperdal) brought to the public as the first antipsychotic med. since Clozapine and a big breakthrough in safety, specificity and effectiveness (especially for 'negative symptoms') and so deserving a whole new extra name - Atypical - risperdal showed, like haloperidol, high binding affinity for dopamine-D2 receptors and rapid dissociation from them. (See: http://jpet.aspetjournals.org/cgi/content/abstract/247/2/661)
This similarity to Haldol, strong binding and rapid dissociation to Dopamine 2 receptors in the brain, was sought after and developed by them during the chemical design of the product. And, it is interesting to note that Risperdal is named after Haldal as well as the test chemcal the had prior to naming Risperidone/Risperal which had a chemical desgination that started with the letter R.
The atypicals were a major breakthrough in propaganda, sales and profit. Amphetamine type drugs for the kids has been a 50 year triump as well. Slow but steady each decade has seen greater numbers of children drugged and ever increasing profit.
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