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General News    H4'ed 12/23/13

Avoid Vitamins Says Editorial in Annals

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Certain drugs may be dangerous when used outside of acceptable dosage ranges, and similarly, some commonly used vitamins may produce toxicity when dosage is excessive.  For example, Vitamin D, selenium and Vitamin B6 may all produce symptoms of toxicity when used in excess of recommended dosage ranges.  

Some supplements may have blood thinning effects such as Fish Oil and vitamin E which can produce bleeding which may become fatal.   Some supplements may counteract the effect of drugs.  An example is the effect of Vitamin K which counteracts the blood thinner medication coumadin (warfarin) commonly used to treat atrial fibrillation and deep venous thrombosis.

Quality of Supplements May Vary

The quality of supplements may vary considerably, depending on site of origin and manufacturer.  The cheaper supplements may contain ingredients which are less biologically active,  or may contain adulterated or undesirable ingredients such as preservatives, fillers, soy, GMO, dairy, and wheat gluten.  Higher quality supplements from reputable sources are usually more expensive.   It may be advisable to seek guidance from a knowledgeable heath care practitioner regarding which supplements to use.

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Links and References

1) http://annals.org/article.aspx?articleid=1789253
Eliseo Guallar, SaverioStranges, Cynthia Mulrow, Lawrence J. Appel, Edgar R. Miller, III; Enough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements. Annals of Internal Medicine. 2013 Dec;159(12):850-851.

2) http://annals.org/article.aspx?articleid=1789248
17 December 2013   Oral High-Dose Multivitamins and Minerals After Myocardial Infarction: A Randomized Trial
Gervasio A. Lamas, MD; Robin Boineau, MD, MA; Christine Goertz, DC,

3) http://annals.org/article.aspx?articleid=1789250
17 December 2013  Long-Term Multivitamin Supplementation and Cognitive Function in Men: A Randomized Trial
Francine Grodstein, ScD*; Jacqueline O'Brien, ScD*; Jae Hee Kang, ScD; Rimma Dushkes, PhD; Nancy R. Cook, ScD; Olivia Okereke, MD; JoAnn E.

4) http://annals.org/article.aspx?articleid=1767855
17 December 2013
Vitamin and Mineral Supplements in the Primary Prevention of Cardiovascular Disease and Cancer: An Updated Systematic Evidence Review for the U.S. Preventive Services Task Force
Stephen P. Fortmann, MD; Brittany U. Burda, MPH; Caitlyn A. Senger, MPH; Jennifer S. Lin, MD, MCR; and Evelyn P. Whitlock, MD, MPH

5) http://ajcn.nutrition.org/content/79/5/805.full
Am J Clin Nutr May 2004 vol. 79 no. 5 805-811
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial1,2,3
Katherine L Tucker,    Beth Olson,    Peter Bakun,    Gerard E Dallal,    Jacob Selhub, and    Irwin H Rosenberg

6) http://now.tufts.edu/news-releases/mild-b12-deficiency-cognition
Mild Vitamin B12 Deficiency Associated with Accelerated Cognitive Decline  December 5, 2012   Andrea Grossman

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Jeffrey Dach MD is a physician and author of three books, Natural Medicine 101, and Bioidentical Hormones 101, and Heart Book all available on Amazon, or as a free e-book on his web sites. Dr. Dach is founder and chief medical officer of (more...)
 

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